Concepedia

A remarkable rate acceleration of the Baylis–Hillman reaction

Wei-Der Lee, Kung‐Shuo Yang, Kwunmin Chen

Chemical Communications · 2001 · 50 citations · 15 references

DOI

Concepts

Abstract

Treatment of alpha-naphthyl acrylate with both aliphatic and aromatic aldehydes in the presence of DABCO (30 mol%) afforded the desired (alpha-methylene-beta-hydroxy)esters with reasonable chemical yields (51-88%) within 20 min.

References

15

The Baylis-Hillman reaction: A novel carbon-carbon bond forming reaction

Deevi Basavaiah, Polisetti Dharma Rao, Rachakonda Suguna Hyma · Tetrahedron · 1996 · 858 citations

, , +2

Synthetic potential of the tertiary-amine-catalysed reaction of activated vinyl carbanions with aldehydes

Siegfried E. Drewes, Gregory Roos · Tetrahedron · 1988 · 677 citations

, , +3

Chiral Amine-Catalyzed Asymmetric Baylis<i>−</i>Hillman Reaction:  A Reliable Route to Highly Enantiomerically Enriched (α-Methylene-β-hydroxy)esters

Yoshiharu Iwabuchi, Mari Nakatani, N. Yokoyama et al. · Journal of the American Chemical Society · 1999 · 408 citations

, , +6

New Strategies for the Development of an Asymmetric Version of the Baylis–Hillman Reaction

Peter Langer · Angewandte Chemie International Edition · 2000 · 401 citations

, , +10

The Asymmetric Baylis−Hillman Reaction

Linda Joy Brzezinski, Sara Rafel, James W. Leahy · Journal of the American Chemical Society · 1997 · 198 citations

, , +4