Uncoupling Store-Operated Ca2+ Entry and Altered Ca2+ Release from Sarcoplasmic Reticulum through Silencing of Junctophilin Genes

Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx

Clotilde Randriamampita, Roger Y. Tsien · Nature · 1993 · 880 citations

Ca2+ Influx, Signal Transduction, Physiology +10

JunctophilinsA Novel Family of Junctional Membrane Complex Proteins

Hiroshi Takeshima · Molecular Cell · 2000 · 587 citations

Protein Secretion, Protein Function, Natural Sciences +6

Role of Troponin I Proteolysis in the Pathogenesis of Stunned Myocardium

Wei Dong Gao, Dan Atar, Yongge Liu et al. · Circulation Research · 1997 · 389 citations

Cardiac Muscle, Heart Failure, Stunned Myocardium +17

Increased Activity of Calcium Leak Channels in Myotubes of Duchenne Human and <i>mdx</i> Mouse Origin

Peying Fong, Paul R. Turner, Wilfred F. Denetclaw et al. · Science · 1990 · 355 citations

A repeat expansion in the gene encoding junctophilin-3 is associated with Huntington disease–like 2

Susan E. Holmes, Elizabeth O’Hearn, Adam Rosenblatt et al. · Nature Genetics · 2001 · 283 citations

Neurodegenerative Diseases, Genetic Disorder, Genetics +9