Halogen Bonding in Supramolecular Chemistry

TLDR

Halogen bonding is a noncovalent interaction where halogen atoms act as electrophilic species, characterized by specific energetic and geometrical features that influence intermolecular recognition and self‑assembly across diverse research fields. The study presents principles for crystal engineering using halogen‑bonding interactions. The authors outline these principles to guide crystal design that exploits halogen bonding. Halogen bonding’s potential is demonstrated in applications to liquid crystals, magnetic and conducting materials, and biological systems.

Abstract

Halogen bonding is the noncovalent interaction where halogen atoms function as electrophilic species. The energetic and geometrical features of the interaction are described along with the atomic characteristics that confer molecules with the specific ability to interact through this interaction. Halogen bonding has an impact on all research fields where the control of intermolecular recognition and self-assembly processes plays a key role. Some principles are presented for crystal engineering based on halogen-bonding interactions. The potential of the interaction is also shown by applications in liquid crystals, magnetic and conducting materials, and biological systems.