Concepedia

Pilot trial of genetically modified, attenuated Salmonella expressing the E. coli cytosine deaminase gene in refractory cancer patients

John Nemunaitis, Casey Cunningham, Neil Senzer, Joseph A. Kuhn, Jennifer Cramm, Craig E. Litz, Robert Cavagnolo, Ann Cahill, Caroline Clairmont, Mario Sznol

Cancer Gene Therapy · 2003 · 338 citations · 30 references

DOI

Concepts

References

30

Construction of an eae deletion mutant of enteropathogenic Escherichia coli by using a positive-selection suicide vector

Michael S. Donnenberg, James B. Kaper · Infection and Immunity · 1991 · 1.1K citations · Full text

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Phase I Study of the Intravenous Administration of Attenuated<i>Salmonella typhimurium</i>to Patients With Metastatic Melanoma

John Toso, Vee J. Gill, Patrick Hwu et al. · Journal of Clinical Oncology · 2002 · 712 citations

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Phase I Study of the Intravenous Administration of Attenuated Salmonella typhimurium to Patients With Metastatic Melanoma

John Toso · Journal of Clinical Oncology · 2002 · 629 citations

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Tumor-targeted Salmonella as a novel anticancer vector.

John M. Pawelek, K. Brooks Low, David Bermudes · PubMed · 1997 · 527 citations

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Lipid A mutant Salmonella with suppressed virulence and TNFα induction retain tumor-targeting in vivo

K. Brooks Low, Martina Ittensohn, Trung Bao Le et al. · Nature Biotechnology · 1999 · 476 citations

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