Concepedia

Treatment of Chronic, Noninfectious, Nonnecrotizing Scleritis with Tumor Necrosis Factor Alpha Inhibitors

Ashwinee Ragam, Anton M. Kolomeyer, Christina H. Fang, Yinfei Xu, David Chu

Ocular Immunology and Inflammation · 2013 · 39 citations · 28 references

DOI

Abstract

TNF-alpha inhibitors appear to have a role in managing non-infectious, non-necrotizing scleritis refractory to initial therapy, mainly by reducing inflammation and decreasing concurrent CS use.

References

28

Golimumab, a new human tumor necrosis factor α antibody, administered every four weeks as a subcutaneous injection in psoriatic arthritis: Twenty‐four–week efficacy and safety results of a randomized, placebo‐controlled study

Arthur Kavanaugh, Iain B. McInnes, Philip J. Mease et al. · Arthritis & Rheumatism · 2009 · 595 citations

Episcleritis and scleritis: clinical features and treatment results

Douglas A. Jabs, Abdulbaki Mudun, James P. Dunn et al. · American Journal of Ophthalmology · 2000 · 386 citations

, , +5

Differential efficacy of tumor necrosis factor inhibition in the management of inflammatory eye disease and associated rheumatic disease

Justine R. Smith, Ralph D. Levinson, Gary N. Holland et al. · Arthritis & Rheumatism · 2001 · 330 citations

Tumor necrosis factor α blockade with infliximab for refractory uveitis and scleritis

Conor C. Murphy, William Ayliffe, A. D. Booth et al. · Ophthalmology · 2004 · 188 citations

, , +7

Low-dose Methotrexate Therapy for Ocular Inflammatory Disease

Sanjay S. Shah, Careen Y. Lowder, Michael Schmitt et al. · Ophthalmology · 1992 · 182 citations

, , +4