Uremia-Specific Effects in the Arterial Media During Development of Uremic Atherosclerosis in Apolipoprotein E–Deficient Mice

Susanne Bro, Rehannah Borup, Claus B. Andersen, Flemming Moeller, Klaus Ølgaard, Lars B. Nielsen

Arteriosclerosis Thrombosis and Vascular Biology · 2005 · 29 citations · 20 references

Abstract

The results suggest that uremic vasculopathy in apoE(-/-) mice, in addition to intimal atherosclerosis, is characterized by a uremia-specific medial smooth muscle cell degeneration, which appears to be accentuated by hypercholesterolemia.

References

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