A SYNDROME CHARACTERIZED BY ESTROGENIC INSUFFICIENCY, GALACTORRHEA AND DECREASED URINARY• GONADOTROPIN*

Abstract

IN 1932, Ahumada and del Castillo (1) published the history of a patient presenting galactorrhea and amenorrhea with symptoms of estrogenic insufficiency and absence of urinary gonadotropins. To this observation, the first to our knowledge, other studies made during the last years in the Endocrinology Service of the Rivadavia Hospital have been added. In these new cases the existence was verified of galactorrhea with amenorrhea and urinary gonadotropin (FSH) decreased below 6 mouse units in twenty-four hours. At this stage of our observations we were informed that at the meeting of the Association for the Study of Internal Secretions held in Atlantic City in June 1951, a communication was presented by Forbes, Henneman, Griswold and Albright under the title “A syndrome, distinct from acromegaly, characterized by spontaneous lactation, amenorrhea, and low follicle-stimulating hormone excretion.” Of this paper, we know only the abstract published in the July 1951 issue of The Journal of Clinical Endocrinology (2).