Predictive value of serum interleukin-6 level in influenza virus–associated encephalopathy

On the cellular source and function of interleukin 6 produced in the central nervous system in viral diseases

Karl Frei, Ursula Malipiero, Thomas Leist et al. · European Journal of Immunology · 1989 · 686 citations

Local and systemic cytokine responses during experimental human influenza A virus infection. Relation to symptom formation and host defense.

Frederick G. Hayden, Roschelle Fritz, M C Lobo et al. · Journal of Clinical Investigation · 1998 · 679 citations · Full text

Asthma, Nasal Lavage Fluids, Inflammatory Lung Disease +20

Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis

Bin Cheng, Sylvia Christakos, Mark P. Mattson · Neuron · 1994 · 668 citations

Inflammation, Energy Homeostasis, Neurophysiology +12

The influence of cytokines on the integrity of the blood-brain barrier in vitro

Helga E. de Vries, Margret C.M. Blom-Roosemalen, Marijke van Oosten et al. · Journal of Neuroimmunology · 1996 · 665 citations

Inflammation, Blood–brain Barrier, Immunology +10

Production of tumor necrosis factor-alpha by microglia and astrocytes in culture

Makoto Sawada, Noriaki Kondo, Akio Suzumura et al. · Brain Research · 1989 · 627 citations

Inflammation, Neuro-oncology, Medicine +10