Stimulating the Central Nervous System to Prevent Intestinal Dysfunction After Traumatic Brain Injury

Abstract

In a mouse model of TBI, vagal stimulation prevented TBI-induced intestinal permeability. Furthermore, vagal stimulation increased enteric glial activity and may represent the pathway for central nervous system regulation of intestinal permeability.

References

Page 1

	Year	Citations
Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin L. V. Borovikova, Svetlana Ivanova, Minghuang Zhang, Nature InflammationAllergyAutoimmune DiseaseMedicineImmunology	2000	4K
Nicotinic acetylcholine receptor α7 subunit is an essential regulator of inflammation Hong Wang, Man Yu, Mahendar Ochani, Nature InflammationMolecular PhysiologyMedicineEssential RegulatorNicotine	2002	3.1K
Fulminant Jejuno-Ileitis following Ablation of Enteric Glia in Adult Transgenic Mice Toby G. Bush, Tor Savidge, Tom C. Freeman, Cell Fulminant Jejuno-ileitisMucosal ImmunologyFunctional Gastrointestinal DisorderPathogenesisImmunology	1998	583
Multiple Organ Failure Syndrome in the 1990s Alan L. Beal JAMA InflammationMetabolic SyndromeTranslational MedicineHeart FailureTarget-organ Damage	1994	538
Prospective, randomized, controlled trial to determine the effect of early enhanced enteral nutrition on clinical outcome in mechanically ventilated patients suffering head injury Stephen J. Taylor, S. B. Fettes, Claire Jewkes, Critical Care Medicine	1999	407
A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease Yevgeny Zolotarevsky, Gail Hecht, Athanasia Koutsouris, Gastroenterology Membrane-permeant PeptideSignal TransductionMlc KinaseCell SignalingImmunology	2002	379
Nutritional stimulation of cholecystokinin receptors inhibits inflammation via the vagus nerve Misha Luyer, Jan Greve, M’hamed Hadfoune, The Journal of Experimental Medicine	2005	293
Experimental Closed Head Injury: Analysis of Neurological Outcome, Blood–Brain Barrier Dysfunction, Intracranial Neutrophil Infiltration, and Neuronal Cell Death in Mice Deficient in Genes for Pro-Inflammatory Cytokines Philip F. Stahel, Esther Shohami, Firas Younis, Journal of Cerebral Blood Flow & Metabolism Traumatic Brain InjuryImmunologyImmune RegulationCell DeathHead Injury	2000	272
Outcomes and Costs of Acute Treatment of Traumatic Brain Injury Lisa J. McGarry, David R. Thompson, Frederick H. Millham, The Journal of Trauma: Injury, Infection, and Critical Care	2002	195
Beta-Blocker Exposure is Associated With Improved Survival After Severe Traumatic Brain Injury Bryan A. Cotton, Kimberly Snodgrass, Sloan B. Fleming, The Journal of Trauma: Injury, Infection, and Critical Care	2007	182

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