Massive Intravenous Immunoglobulin Treatment in Women with Four or More Recurrent Spontaneous Abortions of Unexplained Etiology: Down‐Regulation of NK Cell Activity and Subsets

Mamoru Morikawa, Hideto Yamada, Emi H. Kato, Shigeki Shimada, Tatsuro Kishida, Takahiro Yamada, Seiichiro Fujimoto, Gén Kobashi

American Journal of Reproductive Immunology · 2001 · 58 citations · 0 references

Abstract

MIVIg treatment was effective in all 14 pregnancies from RSA women of unexplained etiology, excluding 4 abortions with chromosome abnormality. Peripheral NK cell activity and subsets were suppressed by MIVIg treatment.