Distribution, Metabolism, and Excretion of a Novel Surface‐Active Agent, Purified Poloxamer 188, in Rats, Dogs, and Humans

Purified Poloxamer 188 for Treatment of Acute Vaso-occlusive Crisis of Sickle Cell Disease

Eugene P. Orringer, James F. Casella, Kenneth I. Ataga et al. · JAMA · 2001 · 197 citations

Medicine, Hematology, Pharmacotherapy +13

CYP2D6- and CYP3A-dependent metabolism of dextromethorphan in humans

Évelyne Jacqz-Aigrain, Christian Funck‐Brentano, Thierry Cresteil · Pharmacogenetics · 1993 · 144 citations

Medicine, Biochemistry, Pharmacology +14

RheothRx (Poloxamer 188) Injection for the Acute Painful Episode of Sickle Cell Disease: A Pilot Study

Patricia Adams‐Graves, Amos Kedar, Mabel Koshy et al. · Blood · 1997 · 113 citations

Medicine, Hematology, Pharmacotherapy +6

Distribution and Elimination of Coated Polymethyl [2-14C]Methacrylate Nanoparticles After Intravenous Injection in Rats

Daniel Leu, Barbara Manthey, Jörg Kreuter et al. · Journal of Pharmaceutical Sciences · 1984 · 88 citations

Pharmacy, Pharmaceutics, Pharmacokinetics +12

Pluronic F-68 reduces the endothelial adherence and improves the rheology of liganded sickle erythrocytes.

C M Smith, Robert P. Hebbel, David P. Tukey et al. · PubMed · 1987 · 59 citations

Veterinary Medicine, Biomedical Engineering, Cell Biology +14