Concepedia

Postnatal erythropoietin treatment mitigates neural cell loss after systemic prenatal hypoxic-ischemic injury

Marcus D. Mazur, Robert H. Miller, Shenandoah Robinson

Journal of Neurosurgery Pediatrics · 2010 · 98 citations · 55 references

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Abstract

These data demonstrate that neonatal rhEPO administration in a novel clinically relevant paradigm initiated 4 days after a global prenatal hypoxic-ischemic insult in rats rescues neural cells, and induces lasting histological and functional improvement in adult rats.

References

55

A new mathematical model for relative quantification in real-time RT-PCR

Michael W. Pfaffl · Nucleic Acids Research · 2001 · 34.3K citations · Full text

Erythropoietin crosses the blood–brain barrier to protect against experimental brain injury

Michael Brines, Pietro Ghezzi, Sonja Keenan et al. · Proceedings of the National Academy of Sciences · 2000 · 1.4K citations · Full text

Erythropoietin prevents neuronal apoptosis after cerebral ischemia and metabolic stress

Anna‐Leena Sirén, Maddalena Fratelli, Michael Brines et al. · Proceedings of the National Academy of Sciences · 2001 · 1K citations · Full text

Sensitivity to leptin and susceptibility to seizures of mice lacking neuropeptide Y

Jay C. Erickson, Kathy E. Clegg, Richard D. Palmiter · Nature · 1996 · 1K citations

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Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-κB signalling cascades

Murat Digicaylioglu, Stuart A. Lipton · Nature · 2001 · 928 citations

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