Possible involvement of activation of P53/P21 and demethylation of RUNX 3 in the cytotoxicity against Lovo cells induced by 5-Aza-2′-deoxycytidine

A gene hypermethylation profile of human cancer.

Manel Esteller, Paul G. Corn, Stephen B. Baylin et al. · PubMed · 2001 · 2K citations

Medicine, Molecular Biology, Oncology +17

Causal Relationship between the Loss of RUNX3 Expression and Gastric Cancer

Qing-Lin Li, Kosei Ito, Chohei Sakakura et al. · Cell · 2002 · 1K citations · Full text

Medicine, Cancer Biology, Oncology +14

Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer

Simone Fulda, Martin U Küfer, Éric Meyer et al. · Oncogene · 2001 · 403 citations

Life Sciences, Cell Biology, Molecular Biology +16

DNA Methylation Inhibitor 5-Aza-2′-Deoxycytidine Induces Reversible Genome-Wide DNA Damage That Is Distinctly Influenced by DNA Methyltransferases 1 and 3B

Stela S. Palii, Beth O. Van Emburgh, Umesh T. Sankpal et al. · Molecular and Cellular Biology · 2007 · 380 citations · Full text

Medicine, Cancer Biology, Oncology +17

Resistance to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in neuroblastoma cells correlates with a loss of caspase-8 expression.

Angelika Eggert, Michael A. Grotzer, Tycho Jan Zuzak et al. · PubMed · 2001 · 270 citations

Life Sciences, Oncology, Pharmacology +17