Leflunomide or Methotrexate for Juvenile Rheumatoid Arthritis

Earl D. Silverman, Richard Mouy, Lynn Spiegel, Lawrence Jung, Rotraud K. Saurenmann, Pekka Lahdenne, Gerd Horneff, Immaculada Calvo, Ilona S. Szer, Karen Simpson,

New England Journal of Medicine · 2005 · 255 citations · 19 references

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Abstract

In patients with polyarticular juvenile rheumatoid arthritis, methotrexate and leflunomide both resulted in high rates of clinical improvement, but the rate was slightly greater for methotrexate. At the doses used in this study, methotrexate was more effective than leflunomide.

References

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