Concepedia

Anti–IL-5 (mepolizumab) therapy induces bone marrow eosinophil maturational arrest and decreases eosinophil progenitors in the bronchial mucosa of atopic asthmatics

Andrew Menzies‐Gow, Patrick Flood-Page, Roma Sehmi, John Burman, Qutayba Hamid, Douglas S. Robinson, A B Kay, Judah A. Denburg

Journal of Allergy and Clinical Immunology · 2003 · 271 citations · 24 references

DOIFull text

Open access

Concepts

References

24

Predominant T<sub>H2</sub>-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma

Douglas S. Robinson, Qutayba Hamid, Sun Ying et al. · New England Journal of Medicine · 1992 · 2.8K citations

Eosinophilic Inflammation in Asthma

Jean Bousquet, Pascal Chanez, Jean Yves Lacoste et al. · New England Journal of Medicine · 1990 · 2.5K citations · Full text

Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsìveness, and the late asthmatic response

Margaret J Leckie, Anneke Ten Brinke, Jamey Khan et al. · The Lancet · 2000 · 1.8K citations

, , +6

Differentiation and proliferation of hematopoietic stem cells

Megumu Ogawa · Blood · 1993 · 1.4K citations

Eosinophil's Role Remains Uncertain as Anti–Interleukin-5 only Partially Depletes Numbers in Asthmatic Airway

Patrick Flood-Page, Andrew Menzies‐Gow, A B Kay et al. · American Journal of Respiratory and Critical Care Medicine · 2003 · 804 citations