Anti–IL-5 (mepolizumab) therapy induces bone marrow eosinophil maturational arrest and decreases eosinophil progenitors in the bronchial mucosa of atopic asthmatics

Predominant T_H2-like Bronchoalveolar T-Lymphocyte Population in Atopic Asthma

Douglas S. Robinson, Qutayba Hamid, Sun Ying et al. · New England Journal of Medicine · 1992 · 2.8K citations

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Eosinophilic Inflammation in Asthma

Jean Bousquet, Pascal Chanez, Jean Yves Lacoste et al. · New England Journal of Medicine · 1990 · 2.5K citations · Full text

Veterinary Medicine, Immunology, Pathology +14

Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsìveness, and the late asthmatic response

Margaret J Leckie, Anneke Ten Brinke, Jamey Khan et al. · The Lancet · 2000 · 1.8K citations

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Differentiation and proliferation of hematopoietic stem cells

Megumu Ogawa · Blood · 1993 · 1.4K citations

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Eosinophil's Role Remains Uncertain as Anti–Interleukin-5 only Partially Depletes Numbers in Asthmatic Airway

Patrick Flood-Page, Andrew Menzies‐Gow, A B Kay et al. · American Journal of Respiratory and Critical Care Medicine · 2003 · 809 citations

Medicine, Immunology, Pharmacology +15