Directed Branched‐Regioselective Hydroformylation of 2‐Substituted Allylic <i>o</i>‐DPPB Esters

Abstract

Abstract Branched‐regioselective hydroformylation of allylic o ‐DPPB esters has been accomplished with mono‐ and disubstituted alkene functions in good to excellent yields and selectivities. Optimized reaction conditions allowed the reaction of even trisubstitued alkenic functions. These reactions occur as a result of a significant rate‐accelerating effect exerted by the catalyst‐directing o ‐DPPB group, as exemplified by highly position‐, regio‐, and diastereoselective hydroformylation of the geranyl and neryl o ‐DPPB esters.(© Wiley‐VCH Verlag GmbH &amp; Co. KGaA, 69451 Weinheim, Germany, 2007)