Effects of the aldose reductase inhibitor sorbinil on the isolated cultured rat lens

Formation of Polyols by the Lens of the Rat with ‘Sugar’ Cataract

Ruth van Heyningen · Nature · 1959 · 435 citations

Medicine, Biochemistry, Ophthalmology +9

Polyol Accumulation in Galactosemic and Diabetic Rats: Control by an Aldose Reductase Inhibitor

D. Dvornik, N. Simard-Duquesne, M. Krami et al. · Science · 1973 · 266 citations

Medicine, Biochemistry, Pharmacology +14

Diabetic Cataracts and Flavonoids

S.D. Varma, A Mizuno, J. H. Kinoshita · Science · 1977 · 189 citations

Medicine, Biochemistry, Ophthalmology +9

Action of Sorbinil in Diabetic Peripheral Nerve: Relationship of Polyol (Sorbitol) Pathway Inhibition to a <i>myo</i>-Inositol-mediated Defect in Sodium-Potassium ATPase Activity

Douglas A. Greene, S. A. Lattimer · Diabetes · 1984 · 176 citations

Medicine, Biochemistry, Pharmacology +16

CP-45,634: A novel aldose reductase inhibitor that inhibits polyol pathway activity in diabetic and galactosemic rats

M.J. Peterson, Reinhard Sarges, Charles E. Aldinger et al. · Metabolism · 1979 · 137 citations

Life Sciences, Biochemistry, Pharmacology +13