Concepedia

Various Penetrance of Familial Medullary Thyroid Carcinoma in Patients With RET Protooncogene Codon 790/791 Germline Mutations

Guido Fitze, Ingrid Anne Mandy Schierz, Jan Bredow, H. D. Saeger, D. Roesner, Hans K. Schackert

Annals of Surgery · 2002 · 56 citations · 25 references

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Abstract

Codon 790/791 mutations had diverse penetrance. Whereas prophylactic thyroidectomy in children is a justifiable approach for codon 790 mutation carriers, the indication for thyroidectomy should depend on the clinical course of codon 791 carriers.

References

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