Association Between the Expression of Aggrecan and the Distribution of Aggrecan Gene Variable Number of Tandem Repeats With Symptomatic Lumbar Disc Herniation in Chinese Han of Northern China

Abstract

The findings suggest a relation between aggrecan and symptomatic LDH, where symptomatic LDH has a lower tendency of allele repeats. In addition, this study observed an association between the distribution of aggrecan gene VNTR polymorphism and the expression of aggrecan in symptomatic LDH.