Concepedia

Synthesis and efficacy of 1-[bis(4-fluorophenyl)-methyl]piperazine derivatives for acetylcholinesterase inhibition, as a stimulant of central cholinergic neurotransmission in Alzheimer’s disease

C. T. Sadashiva, Joya Chandra, K.C. Ponnappa, T. Veerabasappa Gowda, Kanchugarakoppal S. Rangappa

Bioorganic & Medicinal Chemistry Letters · 2006 · 47 citations · 9 references

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References

9

A new and rapid colorimetric determination of acetylcholinesterase activity

George L. Ellman, K. Diane Courtney, Valentino Andres et al. · Biochemical Pharmacology · 1961 · 26.6K citations

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Structure of acetylcholinesterase complexed with E2020 (Aricept®): implications for the design of new anti-Alzheimer drugs

Gitay Kryger, Israel Silman, Joel L. Sussman · Structure · 1999 · 727 citations · Full text

, , +12

Drug Discovery and Evaluation

HG Vogel · Biomedicine & Pharmacotherapy · 1998 · 427 citations

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Structure-based 3D QSAR and design of novel acetylcholinesterase inhibitors

Wolfgang Sippl, Jean‐Marie Contreras, Isabelle Parrot et al. · Journal of Computer-Aided Molecular Design · 2001 · 84 citations

Evidence for GABA-BZ receptor modulation in short-term memory passive avoidance task paradigm in mice.

A C Sharma, S. K. Kulkarni · PubMed · 1990 · 44 citations

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