The Intra- and Intermolecular Pauson-Khand Reaction Promoted by Alkyl Methyl Sulfides

Abstract

The Pauson-Khand reaction was promoted by the addition of alkyl methyl sulfides. Among the sulfides, the ones having primary and secondary alkyl groups were more effective than those with tertiary alkyl groups. The intermolecular cyclization with simple alkenes makes the use of n-butyl methyl sulfide as the best method to carry out the stoichiometric Pauson-Khand reaction.