The Impact of Cell Density and Mutations in a Model of Multidrug Resistance in Solid Tumors

A mathematic model for relating the drug sensitivity of tumors to their spontaneous mutation rate.

Goldie Jh, Coldman Aj · PubMed · 1980 · 1.3K citations

Medicine, Cancer Biology, Oncology +16

Dynamics of Tumor Growth

Anna Kane Laird · British Journal of Cancer · 1964 · 868 citations · Full text

Medicine, Cancer Biology, Oncology +12

β4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

Valerie M. Weaver, Sophie A. Lelièvre, Johnathon N. Lakins et al. · Cancer Cell · 2002 · 794 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer

Antonija Kreso, Catherine O′Brien, Peter van Galen et al. · Science · 2012 · 740 citations · Full text

Medicine, Cancer Biology, Oncology +17

Mechanisms of Multidrug Resistance in Cancer

Jean‐Pierre Gillet, Michael M. Gottesman · Methods in molecular biology · 2009 · 687 citations

Medicine, Oncology, Pharmacology +12