Insights into the role of anaplerosis in insulin secretion: a 13C NMR study

Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis

Pierre Maechler, Claes B. Wollheim · Nature · 1999 · 505 citations · Full text

Signal Transduction, Mitochondrial Function, Biochemistry +8

Evaluation of carbon flux and substrate selection through alternate pathways involving the citric acid cycle of the heart by 13C NMR spectroscopy.

Craig R. Malloy, A. Dean Sherry, F. Mark H. Jeffrey · Journal of Biological Chemistry · 1988 · 325 citations · Full text

Cardiac Muscle, Nmr Spectroscopy, Carbon Flux +21

Glucose-regulated anaplerosis and cataplerosis in pancreatic beta-cells: possible implication of a pyruvate/citrate shuttle in insulin secretion.

Salah Farfari, Volkmar Schulz, Barbara E. Corkey et al. · Diabetes · 2000 · 272 citations · Full text

Metabolic Remodeling, Insulin Signaling, Oxidative Stress +22

¹³ C NMR isotopomer analysis reveals a connection between pyruvate cycling and glucose-stimulated insulin secretion (GSIS)

Danhong Lu, Hindrik Mulder, Piyu Zhao et al. · Proceedings of the National Academy of Sciences · 2002 · 267 citations · Full text

Glucose Responsiveness, Molecular Biology, Mitochondrial Intermediates +19

Oscillations in cytosolic free Ca2+, oxygen consumption, and insulin secretion in glucose-stimulated rat pancreatic islets

Edward Longo, Keith Tornheim, Jude T. Deeney et al. · Journal of Biological Chemistry · 1991 · 214 citations · Full text

Ca2+ Oscillations, Pancreas Transplantation, Cellular Physiology +20