Polymorphism of Pyridine-<i>N</i>-oxide and Its Deuterated Analogues

Abstract

The aggregation of pyridine-N-oxide molecules in the solid state is very sensitive to small changes of the hydrogen/deuterium (H/D) exchange of the molecules and the thermal conditions during the crystallization process. The in situ crystallization of a partial deuterated pyridine-N-oxide allows the characterization of a low-temperature crystallographic phase.