American Journal of Critical Care · 2012 · 32 citations · 6 references
Psychotropic MedicationPsychopharmacologyPharmacotherapySevere AgitationSocial Sciences6-Year-old GirlDrug OverdoseDrug ToxicityDrug SafetyPsychoactive DrugTreat Lisdexamfetamine OverdosePsychiatryNeuropharmacologyPharmacologySerotonin SyndromeSerotonin ToxidromeMedicinePsychopathologyAnesthesiology
A 6-year-old girl displayed symptoms of serotonin syndrome after accidental ingestion of Vyvanse (lisdexamfetamine dimesylate). Dexmedetomidine was administered because of persistent neuromuscular hyperactivity and severe agitation despite initial therapy with benzodiazepines. Some children show a paradoxical reaction to benzodiazepines, and dexmedetomidine has a possible role in the treatment of serotonin syndrome.
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