High activity of acid sphingomyelinase in major depression

Functional rafts in cell membranes

Kai Simons, Elina Ikonen · Nature · 1997 · 9.7K citations

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Regulation of Renal Organic Anion Transporter 3 (SLC22A8) Expression and Function by the Integrity of Lipid Raft Domains and their Associated Cytoskeleton

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The sphingomyelin cycle and the second messenger function of ceramide.

Yusuf A. Hannun · Journal of Biological Chemistry · 1994 · 1.3K citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

CD95 Signaling via Ceramide-rich Membrane Rafts

Heike Grassmé, Andreas Jekle, Andrea Riehle et al. · Journal of Biological Chemistry · 2001 · 628 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

PKC zeta is a molecular switch in signal transduction of TNF‐alpha, bifunctionally regulated by ceramide and arachidonic acid.

Gerhard Müller, Mohammed Akli Ayoub, Peter Störz et al. · The EMBO Journal · 1995 · 501 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11