Exogenous leptin advances puberty in domestic hen

Positional cloning of the mouse obese gene and its human homologue

Yiying Zhang, Ricardo Proenca, Margherita Maffei et al. · Nature · 1994 · 13.3K citations

Obesity, Metabolic Syndrome, Knockout Mouse +10

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

Yael Gavrieli, Yoav Sherman, Shmuel A. Ben‐Sasson · The Journal of Cell Biology · 1992 · 9.5K citations · Full text

Dna Damage, Apoptosis, Dna Analysis +16

Role of leptin in the neuroendocrine response to fasting

Rexford S. Ahima, Daniel Prabakaran, Christos S. Mantzoros et al. · Nature · 1996 · 3.1K citations

Neuroendocrine Response, Medicine, Physiology +7

Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin

Farid Chehab, Mary E. Lim, Ronghua Lu · Nature Genetics · 1996 · 1.5K citations

Obesity, Sterility Defect, Infertility +11

Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency

I. Sadaf Farooqi, Giuseppe Matarese, Graham M. Lord et al. · Journal of Clinical Investigation · 2002 · 1.3K citations · Full text