Xenopus laevis POU91 protein, an Oct3/4 homologue, regulates competence transitions from mesoderm to neural cell fates

Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cells

Hitoshi Niwa, Jun‐ichi Miyazaki, Austin Smith · Nature Genetics · 2000 · 3.6K citations

Embryonic Stem Cell, Cell Lineage, Quantitative Expression +9

Formation of Pluripotent Stem Cells in the Mammalian Embryo Depends on the POU Transcription Factor Oct4

Jennifer Nichols, Branko Zevnik, Konstantinos Anastassiadis et al. · Cell · 1998 · 3.4K citations · Full text

Embryonic Stem Cell, Induced Pluripotent Stem Cell, Developmental Biology +10

Expression of a dominant negative mutant of the FGF receptor disrupts mesoderm formation in xenopus embryos

Enrique Amaya, Thomas J. Musci, Marc W. Kirschner · Cell · 1991 · 1.1K citations

Signal Transduction, Developmental Biology, Tissue Development +11

A POU-domain transcription factor in early stem cells and germ cells of the mammalian embryo

Mitchell H. Rosner, M Viganò, Keiko Ozato et al. · Nature · 1990 · 919 citations

Germ Cell Biology, Embryonic Stem Cell, Transcriptional Regulation +15

New type of POU domain in germ line-specific protein Oct-4

Hans R. Schöler, Siegfried Ruppert, Noriaki Suzuki et al. · Nature · 1990 · 754 citations · Full text

Protein Function, Protein Expression, Molecular Biology +3