NMDAR-nNOS generated zinc recruits PKCγ to the HINT1–RGS17 complex bound to the C terminus of Mu-opioid receptors

Protein kinase Cα activates RAF-1 by direct phosphorylation

Walter Kölch, Gisela Heidecker, Georg Kochs et al. · Nature · 1993 · 1.3K citations

Signal Transduction, Direct Phosphorylation, Signaling Pathway +5

Chelerythrine is a potent and specific inhibitor of protein kinase C

Jean‐Marc Herbert, Jean‐Michel Augereau, J. Gleye et al. · Biochemical and Biophysical Research Communications · 1990 · 1.2K citations

Specific Inhibitor, Molecular Pharmacology, Signal Transduction +10

Systematic examination in the rat of brain sites sensitive to the direct application of morphine: Observation of differential effects within the periaqueductal gray

Tony L. Yaksh, Joseph C. Yeung, Thomas A. Rudy · Brain Research · 1976 · 605 citations

Brain Sites, Psychopharmacology, Social Sciences +16

Gz, a guanine nucleotide-binding protein with unique biochemical properties.

Patrick J. Casey, Henry Fong, M I Simon et al. · Journal of Biological Chemistry · 1990 · 290 citations · Full text

Pertussis Toxin, Nucleic Acid Chemistry, Protein Expression +15

Structure-Based Analysis of Catalysis and Substrate Definition in the HIT Protein Family

Christopher D. Lima, Michael G. Klein, Wayne A. Hendrickson · Science · 1997 · 208 citations

Protein Assembly, Structure-based Analysis, Biomolecular Structure Prediction +18