Macro-environment of breast carcinoma: frequent genetic alterations in the normal appearing skins of patients with breast cancer

TGF-ß Signaling in Fibroblasts Modulates the Oncogenic Potential of Adjacent Epithelia

Neil A. Bhowmick, Anna Chytil, David Plieth et al. · Science · 2004 · 1.4K citations

Stromal Cells, Adjacent Epithelia, Pathology +21

Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival

Howard Y. Chang, Dimitry S.A. Nuyten, Julie B. Sneddon et al. · Proceedings of the National Academy of Sciences · 2005 · 982 citations · Full text

Breast Oncology, Engineering, Prognosis +27

Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities between Tumors and Wounds

Howard Y. Chang, Julie B. Sneddon, Ash A. Alizadeh et al. · PLoS Biology · 2004 · 940 citations · Full text

Tumor Biology, Gene Expression Signature, Fibrosis +13

Frequent somatic mutations in PTEN and TP53 are mutually exclusive in the stroma of breast carcinomas

Keisuke Kurose, Kristie Gilley, Satoshi Matsumoto et al. · Nature Genetics · 2002 · 422 citations

Breast Oncology, Somatic Variant, Medicine +9

Concurrent and independent genetic alterations in the stromal and epithelial cells of mammary carcinoma: implications for tumorigenesis.

Farid Moinfar, Yan‐Gao Man, Laurent Arnould et al. · PubMed · 2000 · 404 citations

Breast Oncology, Cancer Pathology, Pathology +18