Concepedia

Propylene Glycol‐Associated Renal Toxicity from Lorazepam Infusion

Ndidi E. Yaucher, Jeffrey Fish, Heidi W. Smith, Jeffrey A. Wells

Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · 2003 · 93 citations · 16 references

DOI

Abstract

The patients' increased serum creatinine concentrations are likely to have resulted from exposure to propylene glycol as a result of lorazepam infusion. Serum osmolality and osmol gap may be useful markers for propylene glycol toxicity.

References

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Poisoning and drug overdose

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Propylene Glycol Toxicity Following Continuous Etomidate Infusion For The Control Of Refractory Cerebral Edema

Michael L. Levy, Margaret Aranda, Vladimir Zelman et al. · Neurosurgery · 1995 · 76 citations

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