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Catastrophic Cardiovascular Adverse Reactions to Protamine Are Nitric Oxide/Cyclic Guanosine Monophosphate Dependent and Endothelium Mediated

InflammationCardiovascular DiseaseReactive Nitrogen SpecieMedicinePhysiologyEndothelial DysfunctionVascular BiologyPharmacotherapyToxicologyEndothelium MediatedCardiovascular ToxicityPharmacologyNitrosative StressOxidative Stress