Catastrophic Cardiovascular Adverse Reactions to Protamine Are Nitric Oxide/Cyclic Guanosine Monophosphate Dependent and Endothelium Mediated

L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation

Richard Palmer, Daryl D. Rees, David Ashton et al. · Biochemical and Biophysical Research Communications · 1988 · 1.3K citations

Molecular Physiology, Biochemistry, Physiological Precursor +9

A specific inhibitor of nitric oxide formation from <scp>l</scp>‐arginine attenuates endothelium‐dependent relaxation

Daryl D. Rees, Richard Palmer, H. F. Hodson et al. · British Journal of Pharmacology · 1989 · 854 citations · Full text

Inhaled Nitric Oxide A Selective Pulmonary Vasodilator of Heparin-Protamine Vasoconstriction in Sheep

Marie-Dominique Fratacci, Claes Frostell, Tong-Yen Chen et al. · Anesthesiology · 1991 · 285 citations · Full text

Nitric Oxide, Pulmonary Hypertension, Thrombosis +19

Protamine

Jan C. Horrow · Anesthesia & Analgesia · 1985 · 284 citations

Dr. Jonathan Mark, Hospital Medicine, Address Correspondence +11

Effects of Protamine Administration after Cardiopulmonary Bypass on Complement, Blood Elements, and the Hemodynamic State

James K. Kirklin, Dennis E. Chenoweth, David C. Naftel et al. · The Annals of Thoracic Surgery · 1986 · 245 citations · Full text

Heart Failure, Cardiac Anaesthesia, Hemodynamic State +8