Corticotropin-releasing factor antagonist reduces emotionality in socially defeated rats via direct neurotropic action

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

Sharon Pellow, Philippe Chopin, Sandra E. File et al. · Journal of Neuroscience Methods · 1985 · 5.7K citations

Experimental Psychopathology, Closed Arm Entries, Stress Hormone +11

Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: A novel test of anxiety in the rat

Sharon Pellow, Sandra E. File · Pharmacology Biochemistry and Behavior · 1986 · 1.5K citations

Experimental Psychopathology, Psychoactive Drug, Psychiatry +14

Effects of alpha-adrenoceptor agonists and antagonists in a maze-exploration model of ?fear?-motivated behaviour

Sheila L. Handley, Siddika Mithani · Naunyn-Schmiedeberg s Archives of Pharmacology · 1984 · 957 citations

Experimental Psychopathology, Behavioral Sciences, Behavioral Neuroscience +13

A new test for aggression in rats without aversive stimulation: Differential effects of d-amphetamine and cocaine

Klaus A. Miczek · Psychopharmacology · 1979 · 392 citations

Substance Abuse, Behavioral Sciences, Differential Effects +12

CRF antagonist reverses the “anxiogenic” response to ethanol withdrawal in the rat

Helen A. Baldwin, Stefanie Rassnick, Jean Rivier et al. · Psychopharmacology · 1991 · 359 citations

Molecular Pharmacology, Substance Abuse, Addiction +12