Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

Dorit Shweiki, Ahuva Itin, Dov Soffer, +1

Nature

AngiogenesisVascular AdaptationPhysiologyHypoxia (Medicine)Vascular Biology +8

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

Peter Carmeliet, Valérie Ferreira, Georg Breier, +13

Nature

Developmental BiologyAngiogenesisGeneticsVascular MalformationMorphogenesis +8

Vascular Endothelial Growth Factor in Ocular Fluid of Patients with Diabetic Retinopathy and Other Retinal Disorders

Lloyd Paul Aiello, Robert L. Avery, Paul G. Arrigg, +11

New England Journal of Medicine

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

Napoleone Ferrara, Karen Carver-Moore, Helen Chen, +6

Nature

Developmental BiologyVegf GeneGeneticsMorphogenesisCell Proliferation +8

Angiopoietin-2, a Natural Antagonist for Tie2 That Disrupts in vivo Angiogenesis

Peter C. Maisonpierre, Chitra Suri, Pamela F. Jones, +10

Science

Requisite Role of Angiopoietin-1, a Ligand for the TIE2 Receptor, during Embryonic Angiogenesis

Chitra Suri, Pamela F. Jones, Sybill Patan, +5

Cell

Signal TransductionDevelopmental BiologyAngiogenesisTie2 ReceptorMorphogenesis +8

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

Guo‐Hua Fong, Janet Rossant, Marina Gertsenstein, +1

Nature

Endothelial Cell PathobiologyAngiogenesisSignal TransductionReceptor Tyrosine KinasePhysiology +8

Vessel Cooption, Regression, and Growth in Tumors Mediated by Angiopoietins and VEGF

Jocelyn Holash, Peter C. Maisonpierre, Debra Compton, +5

Science

ImmunologyPathologyTumor BiologyAngiogenesisOncology +15

Isolation of Angiopoietin-1, a Ligand for the TIE2 Receptor, by Secretion-Trap Expression Cloning

Samuel Davis, Thomas H. Aldrich, Pamela F. Jones, +8

Cell

Molecular PhysiologySignal TransductionAngiogenesisSecretion-trap Expression CloningSignaling Pathway +8

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

Thomas T. Sato, Yuzuru Tozawa, Urban Deutsch, +7

Nature

Receptor TyrosineAngiogenesisSignal TransductionSignaling PathwayReceptor Tyrosine Kinase +8