Polygonatum cyrtonema lectin induces murine fibrosarcoma L929 cell apoptosis and autophagy via blocking Ras–Raf and PI3K–Akt signaling pathways

Plant Lectins: A Composite of Several Distinct Families of Structurally and Evolutionary Related Proteins with Diverse Biological Roles

Els J. M. Van Damme, Willy J. Peumans, Annick Barre et al. · Critical Reviews in Plant Sciences · 1998 · 641 citations

Botany, Genetics, Glycobiology +19

Plant Lectins: A Composite of Several Distinct Families of Structurally and Evolutionary Related Proteins with Diverse Biological Roles

Els J. M. Van Damme · Critical Reviews in Plant Sciences · 1998 · 395 citations

Biology, Plant Biology, Plant Molecular Biology +11

Polygonatum cyrtonema lectin induces apoptosis and autophagy in human melanoma A375 cells through a mitochondria-mediated ROS–p38–p53 pathway

Bo Liu, Yan Cheng, Bo Zhang et al. · Cancer Letters · 2008 · 213 citations

Cancer Research, Cell Autophagy, Medicine +11

Mistletoe lectin activates caspase-8/FLICE independently of death receptor signaling and enhances anticancer drug-induced apoptosis.

Heike Bantel, Ingo H. Engels, Wolfgang Voelter et al. · PubMed · 1999 · 196 citations

Apoptosis, Immunology, Cell Death +17

ERK and JNK mediate TNFα-induced p53 activation in apoptotic and autophagic L929 cell death

Yan Cheng, Feng Qiu, Shin‐ichi Tashiro et al. · Biochemical and Biophysical Research Communications · 2008 · 128 citations

Cell Autophagy, Signal Transduction, Signaling Pathway +9