Nonpeptidic δ-opioid Receptor Agonists Reduce Immobility in the Forced Swim Assay in Rats

Depression: a new animal model sensitive to antidepressant treatments

Roger D. Porsolt, Manuel Pichon, M Jalfre · Nature · 1977 · 4.4K citations

Medicine, Neuroscience, Psychiatry +12

Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants

Michael J. Detke, Michael R. Rickels, Irwin Lucki · Psychopharmacology · 1995 · 1.4K citations

Medicine, Neuroscience, Pharmacology +14

Mice deficient for δ- and μ-opioid receptors exhibit opposing alterations of emotional responses

Dominique Filliol, Sandy Ghozland, Johanna Chluba et al. · Nature Genetics · 2000 · 668 citations

Life Sciences, Neurobiology, Neuroscience +13

β-Endorphin-Induced Changes in Schizophrenic and Depressed Patients

Nathan S. Kline · Archives of General Psychiatry · 1977 · 255 citations

Medicine, Pharmacology, Psychiatry +10

Antidepressant behavioral effects by dual inhibition of monoamine reuptake in the rat forced swimming test

J.-P. Rénéric, Irwin Lucki · Psychopharmacology · 1998 · 249 citations

Medicine, Neuroscience, Pharmacology +15