Concepedia

Hydrogen Sulfide Protects from Colitis and Restores Intestinal Microbiota Biofilm and Mucus Production

Jean‐Paul Motta, Kyle L. Flannigan, Terence A. Agbor, Jennifer Beatty, Rory W. Blackler, Matthew L. Workentine, Gabriela Silva, Rui Wang, André G. Buret, John L. Wallace

Inflammatory Bowel Diseases · 2015 · 209 citations · 36 references

DOIFull text

Open access

Abstract

Our results suggest that H(2)S donors could be used therapeutically during colitis, facilitating correction of microbiota biofilm dysbiosis and mucus layer reconstitution.

References

36

The Calgary Biofilm Device: New Technology for Rapid Determination of Antibiotic Susceptibilities of Bacterial Biofilms

Howard Ceri, Merle S. Olson, Carol A. Stremick et al. · Journal of Clinical Microbiology · 1999 · 2.1K citations · Full text

Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function

John W. Elrod, John W. Calvert, Jo Morrison et al. · Proceedings of the National Academy of Sciences · 2007 · 1.2K citations · Full text

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Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis

Malin Johansson, Jenny K. Gustafsson, Jessica Holmén‐Larsson et al. · Gut · 2013 · 987 citations · Full text

Spatial Organization and Composition of the Mucosal Flora in Patients with Inflammatory Bowel Disease

Alexander Swidsinski, Vera Loening‐Baucke, Laura P. Hale et al. · Journal of Clinical Microbiology · 2005 · 874 citations · Full text

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Hydrogen sulfide is an endogenous modulator of leukocyte‐mediated inflammation

R C O Zanardo, Vincenzo Brancaleone, Eleonora Distrutti et al. · The FASEB Journal · 2006 · 856 citations

, , +16