Acute pulmonary alveolar hypoxia increases lung and plasma endothelin-1 levels in conscious rats

A novel potent vasoconstrictor peptide produced by vascular endothelial cells

Masashi Yanagisawa, Hiroki Kurihara, Sadao Kimura et al. · Nature · 1988 · 10.8K citations

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Vascular endothelial cells synthesize nitric oxide from L-arginine

Richard Palmer, D. Ashton, Salvador Moncada · Nature · 1988 · 4.8K citations

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Pathways of Protein Secretion in Eukaryotes

Regis B. Kelly · Science · 1985 · 1.1K citations

Protein Secretion, Regulated Secretion, Molecular Biology +16

Hypoxia on the pulmonary circulation. How and where it acts.

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Pulmonary Arterial Hypertension, Pulmonary Circulation, Physiology +8

Hypoxia releases a vasoconstrictor substance from the canine vascular endothelium.

Gabor M. Rubanyi, Paul M. Vanhoutte · The Journal of Physiology · 1985 · 456 citations · Full text