Detection of in vivo genotoxicity of 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5H]-furanone (MX) by the alkaline single cell gel electrophoresis (Comet) assay in multiple mouse organs

A simple technique for quantitation of low levels of DNA damage in individual cells

Narendra P. Singh, Michael T. McCoy, Raymond R. Tice et al. · Experimental Cell Research · 1988 · 10.7K citations · Full text

Chromatin, Genome Instability, Dna Damage +14

A microgel electrophoresis technique for the direct quantitation of DNA damage and repair in individual fibroblasts cultured on microscope slides

Narendra P. Singh, Raymond R. Tice, Ralph E. Stephens et al. · Mutation Research/Environmental Mutagenesis and Related Subjects · 1991 · 244 citations

Genome Instability, Dna Damage, Microscopy +9

Ames mutagenicity and concentration of the strong mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone and of its geometric isomer E-2-chloro-3-(dichloromethyl)-4-oxo-butenoic acid in chlorine-treated tap waters

Leif Kronberg, Terttu Vartiaine · Mutation Research/Genetic Toxicology · 1988 · 197 citations

Environmental Chemistry, Engineering, Ames Mutagenicity +13

Determination of the strong mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone in chlorinated drinking and humic waters

Jarl Hemming, Bjarne Holmbom, Markku Reunanen et al. · Chemosphere · 1986 · 190 citations

Environmental Chemistry, Ecotoxicity, Engineering +13

Studies on the potent bacterial mutagen, 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone: aqueous stability, XAD recovery and analytical determination in drinking water and in chlorinated humic acid solutions

John R. Meier, Richard B. Knohl, W. Emile Coleman et al. · Mutation Research/Genetic Toxicology · 1987 · 181 citations

Drinking Water, Engineering, Xad Recovery +11