Letters in Applied Microbiology · 2014 · 65 citations · 22 references
The microbial metabolites in the rumen provide nutritional precursors that are critical for general health and milk production in dairy cows. However, studies of the effect of diet on ruminal microbial metabolism are scant. In our current study, we analysed the ruminal microbial metabolite profile of cows fed different types of roughage. We found that the ruminal microbial metabolite profile of cows fed a mixed-roughage diet differed significantly from that of cows fed a single type of roughage. Certain metabolites, such as acetate, hydrocinnamate and methylamine, were closely correlated with specific types of roughage. Our findings provide insight into the effects of different roughages on ruminal microbial fermentation in dairy cows.
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Jeremy K. Nicholson, John C. Lindon · Nature · 2008 · 1.8K citations
MetaboAnalyst 2.0--a comprehensive server for metabolomic data analysis
Jianguo Xia, Raju K. Mandal, I. Sinelnikov et al. · Nucleic Acids Research · 2012 · 1.1K citations · Full text
Michael Michaud, David L. Denlinger · Journal of Comparative Physiology B · 2007 · 263 citations