Concepedia

Pravastatin attenuates tourniquet-induced skeletal muscle ischemia reperfusion injury

John P Dillon, Alan J. Laing, John Chandler, Jiang H. Wang, Anthony McGuinness, H. P. Redmond

Acta Orthopaedica · 2006 · 38 citations · 17 references

DOIFull text

Open access

Abstract

We feel that pravastatin pre-treatment may be a potential therapeutic intervention for skeletal muscle ischemia reperfusion injury in the clinical setting.

References

17

Nitric oxide: an endogenous modulator of leukocyte adhesion.

Paul Kubes, Motohisa Suzuki, D. Neil Granger · Proceedings of the National Academy of Sciences · 1991 · 3K citations · Full text

, , +17

Stroke protection by 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors mediated by endothelial nitric oxide synthase

Matthias Endres, Ulrich Laufs, Zhihong Huang et al. · Proceedings of the National Academy of Sciences · 1998 · 969 citations · Full text

ENDOTHELIAL CELL AND HEPATOCYTE DEATHS OCCUR BY APOPTOSIS AFTER ISCHEMIA-REPERFUSION INJURY IN THE RAT LIVER1,2

Vivek Kohli, Markus Selzner, John F. Madden et al. · Transplantation · 1999 · 333 citations

Nitric oxide prevents leukocyte adherence: role of superoxide

Jeffrey P. Gaboury, Richard C. Woodman, D. Neil Granger et al. · American Journal of Physiology-Heart and Circulatory Physiology · 1993 · 326 citations

, , +16

Simvastatin Preserves the Ischemic-Reperfused Myocardium in Normocholesterolemic Rat Hearts

Allan M. Lefer, Barry J. Campbell, Yong-Kyoo Shin et al. · Circulation · 1999 · 326 citations · Full text