Concepedia

RANKL in human periapical granuloma: possible involvement in periapical bone destruction

Rolando Vernal, Andrea Dezerega, Nicolás Dutzan, Alejandra Chaparro, Rubén León, Sabrita Chandía, Augusto Silva, Jorge Gamonal

Oral Diseases · 2006 · 85 citations · 23 references

DOIFull text

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Abstract

These data indicate that monocytes synthesized RANKL in periapical granulomas and suggest that RANKL is involved in bone loss associated with periapical lesions.

References

23

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

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Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation

David L. Lacey, Emma Timms, Hong‐Lin Tan et al. · Cell · 1998 · 5.4K citations · Full text

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Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand

Young‐Yun Kong, Ulrich Feige, Iidiko Sarosi et al. · Nature · 1999 · 1.9K citations

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Functional human T-cell immunity and osteoprotegerin ligand control alveolar bone destruction in periodontal infection

Yen-Tung A. Teng, Hai P. Nguyen, Xuijuan Gao et al. · Journal of Clinical Investigation · 2000 · 493 citations · Full text

Receptor activator NF κB ligand (RANKL) and osteoprotegerin (OPG) protein expression in periodontitis

Tania N. Crotti, Malcolm Smith, Robert S. Hirsch et al. · Journal of Periodontal Research · 2003 · 289 citations