On the excitotoxic properties of quinolinic acid, 2,3-piperidine dicarboxylic acids and structurally related compounds

Quinolinic Acid: An Endogenous Metabolite That Produces Axon-Sparing Lesions in Rat Brain

Robert Schwarcz, William O. Whetsell, Richard M. Mangano · Science · 1983 · 1.3K citations

Life Sciences, Neurobiology, Neuroscience +16

Lesion of striatal neurons with kainic acid provides a model for Huntington's chorea

Joseph T. Coyle, Robert Schwarcz · Nature · 1976 · 1.2K citations

Life Sciences, Neurobiology, Neuroscience +14

Quinolinic acid: A potent endogenous excitant at amino acid receptors in CNS

Trevor W. Stone, M.N. Perkins · European Journal of Pharmacology · 1981 · 756 citations

Life Sciences, Neuroscience, Pharmacology +13

Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells

J. Victor Nadler, Bruce W. Perry, Carl W. Cotman · Nature · 1978 · 738 citations

Life Sciences, Neuroscience, Pharmacology +14

Assay of tyrosine hydroxylase by coupled decarboxylation of dopa formed from 1-14C-l-tyrosine

Jack C. Waymire, Richard A. Bjur, Norman Weiner · Analytical Biochemistry · 1971 · 461 citations

Life Sciences, Biochemistry, Enzymology +8