Mammalian neuronal actions of FMRFamide and the structurally related opioid Met-enkephalin- Arg6-Phe7

Identification of two related pentapeptides from the brain with potent opiate agonist activity

Joel W. Hughes, Terry Smith, H. W. Kosterlitz et al. · Nature · 1975 · 3.8K citations

Medicine, Medicinal Chemistry, Pharmacology +13

Structure of a Molluscan Cardioexcitatory Neuropeptide

David A. Price, Michael J. Greenberg · Science · 1977 · 1.1K citations

Life Sciences, Biochemistry, Neuroscience +14

Cloning and sequence analysis of cDNA for bovine adrenal preproenkephalin

Masaharu Noda, Yasuji Furutani, Hideo Takahashi et al. · Nature · 1982 · 936 citations

Life Sciences, Biochemistry, Molecular Biology +8

Molecular cloning establishes proenkephalin as precursor of enkephalin-containing peptides

Ueli Gubler, Peter H. Seeburg, Beth J. Hoffman et al. · Nature · 1982 · 628 citations

Life Sciences, Biochemistry, Molecular Biology +8

Neuronal actions of endorphins and enkephalins among brain regions: a comparative microiontophoretic study.

Roger A. Nicoll, George R. Siggins, Nicholas Ling et al. · Proceedings of the National Academy of Sciences · 1977 · 301 citations · Full text

Medicine, Neuroscience, Pharmacology +16