The Use of Midazolam and Small-Dose Ketamine for Sedation and Analgesia During Local Anesthesia

Abstract

Sedation and analgesia are often provided during local anesthesia. This study demonstrates that a small-dose ketamine infusion in combination with midazolam provided satisfactory intraoperative sedation, analgesia, and amnesia in healthy plastic-surgery patients when it was used to supplement local anesthesia.