Rhodium-Catalyzed Intramolecular Aminocarbonylation of Aryl Halides Using Aldehydes as a Source of Carbon Monoxide

Abstract

Abstract The reaction of N-Ts-(2-bromophenyl)alkylamines with aldehydes in the presence of a catalytic amount of a rhodium complex results in the intramolecular aminocarbonylation of the aryl halides to give five-, six-, and seven-membered benzolactams.