A Model System to Study the Environment-Dependent Expression of the <i>Bet v 1a</i> Gene Encoding the Major Birch Pollen Allergen

Abstract

A model system to study the effect of environmental factors on the expression of the Bet v 1a gene encoding the major birch allergen in pollen was generated. Additionally, we suggest that this system could be used to search for factors that inhibit the activity of the gene in pollen in order to reduce the potential allergenicity of birch trees.