EFFICACY AND COST EFFECTIVENESS OF ORAL GANCICLOVIR IN THE PREVENTION OF CYTOMEGALOVIRUS DISEASE AFTER LUNG TRANSPLANTATION1,2

Abstract

In lung transplant recipients, ganciclovir prophylaxis, either intravenous or oral, is safe, well tolerated, and effective in preventing cytomegalovirus disease. Moreover, ganciclovir prophylaxis seems likely to reduce the incidence of bronchiolitis obliterans syndrome. The oral formulation might be preferable because its convenience and possibly lower costs.