Effects of Calcium-Channel Blockade in Older Patients with Diabetes and Systolic Hypertension

Jaakko Tuomilehto, Daiva Rastenytė, W. H. Birkenhäger, Lutgarde Thijs, Riitta Antikaínen, Christopher J. Bulpitt, Astrid Fletcher, Françoise Forette, Adiv Goldhaber, Paolo Palatini,

New England Journal of Medicine · 1999 · 946 citations · 17 references

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Abstract

Nitrendipine-based antihypertensive therapy is particularly beneficial in older patients with diabetes and isolated systolic hypertension. Thus, our findings do not support the hypothesis that the use of long-acting calcium-channel blockers may be harmful in diabetic patients.

References

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