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Local application of growth factors (insulin-like growth factor-1 and transforming growth factor-β1) from a biodegradable poly(d,l-lactide) coating of osteosynthetic implants accelerates fracture healing in rats

Tissue EngineeringRegenerative MedicineSynthetic Bone SubstituteEngineeringLocal ApplicationRegenerative BiomaterialsBone RepairFracture HealingGrowth FactorsWound HealingBiomedical EngineeringTransforming Growth Factor-β1Matrix BiologyMedicineBiomaterialsOrthopaedic SurgeryBiocompatible MaterialTissue Regeneration